Exposure Assessment for Epidemiology and Hazard

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Exposure Assessment for Epidemiology and Hazard

by: ACGIH


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Topics include: historical exposure reconstruction, retrospective exposure assessment, toxicological meaning, respirable particulate mass, extractable mass, exposure variability, occupational cohort studies, biologic monitoring, biological monitoring results, diesel exhaust exposure, peak exposures, hygiene data, hazard surveillance, occupational health research, exposure distribution, functional decrements, exposure classification, adverse reproductive outcomes, pitch volatiles, aerosol measurement, exposure indices, occupational epidemiology, exposure estimates, ambient exposures, personal samples

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First Sentence:
Atmospheric measurements of hazardous substances, biological monitoring of exposed employees, and medical surveillance are performed against a background of engineering and personnel controls.


Measurement methods



Sampling strategies and exposure durations



Biological markers and sample models for assessing toxicological relationships



Strategies for exposure assessment



Statistical descriptors



What agents should be measured?



How should measurement be performed and what averaging time should be used for the measurement?



What sampling strategy should be employed to characterize exposures across individuals, locations, and time?



What durations of exposure should be characterized?



What statistical descriptors should be used to relate exposure to effect?



Exposure Assessment for Epidemiology and Hazard Control examines various approaches to answering these and other important questions. Other topics discussed include the measurement of current exposures (e.g., vapors, gases, aerosols, and complex mixtures); the application of toxicological relationships, including biological markers and sample models; an epidemiological evaluation of exposure-effect relationships, including new methods for effect evaluation and models for population exposure estimates; and strategies for exposure assessment, such as biological sampling interpretation through toxicokinetic processes. This important new volume contains essential information for industrial hygienists, epidemiologists, occupational health physicians, toxicologists, and immunologists.


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